|
BME Courses
Lower Division Courses
Upper Division Courses
Graduate Courses
| Lower Division
(top of page) |
|
19. Fiat Lux Freshman Seminars.
(1)
|
| Seminar, one hour. Discussion of and critical thinking
about topics of current intellectual importance, taught by faculty
members in their areas of expertise and illuminating many paths of
discovery at UCLA. P/NP grading. |
|
99. Student Research Program. (1 to 2)
|
| Tutorial (supervised research or other scholarly work),
three hours per week per unit. Entry-level research for lower division
students under guidance of faculty mentor. Students must be in good
academic standing and enrolled in minimum of 12 units (excluding this
course). Individual contract required; consult Undergraduate Research
Center. May be repeated. P/NP grading. |
| Upper Division
(top of page) |
|
C101. Introduction to Biomedical
Engineering. (4)
|
| (Formerly numbered 101.) Lecture, four hours; laboratory,
three hours; outside study, five hours. Designed for physical sciences,
life sciences, and engineering students. Instead of presenting a general
overview of biomedical engineering, this course provides an in-depth,
quantitative analysis of a few topics in biomedical engineering. Concurrently
scheduled with course C201. Letter grading. |
|
CM102. Basic Human Biology for Biomedical
Engineers I. (4)
|
| (Formerly numbered M102.) (Same as Physiological Science
CM102.) Lecture, three hours; laboratory, two hours. Preparation:
human molecular biology, biochemistry, and cell biology. Not open
for credit to Physiological Science majors. Broad overview of basic
biological activities and organization of human body in system (organ/tissue)
to system basis, with particular emphasis on molecular basis. Modeling/simulation
of functional aspect of biological system included. Actual demonstration
of biomedical instruments, as well as visits to biomedical facilities.
Concurrently scheduled with course CM202. Letter grading. |
CM103. Basic Human
Biology for Biomedical Engineers II. (4) |
| (Formerly numbered M103.) (Same as Physiological Science
CM103.) Lecture, three hours; laboratory, two hours. Preparation:
human molecular biology, biochemistry, and cell biology. Not open
for credit to Physiological Science majors. Molecular-level understanding
of human anatomy and physiology in selected organ systems (digestive,
skin, musculoskeletal, endocrine, immune, urinary, reproductive).
System-specific modeling/simulations (immune regulation, wound healing,
muscle mechanics and energetics, acid-base balance, excretion). Functional
basis of biomedical instrumentation (dialysis, artificial skin, pathogen
detectors, ultrasound, birth-control drug delivery). Concurrently
scheduled with course CM203. Letter grading. |
CM140. Introduction to Biomechanics.
(4) |
| (Formerly numbered M140.) (Same as Mechanical and Aerospace
Engineering CM140.) Lecture, four hours; outside study, eight hours.
Requisites: Mechanical and Aerospace Engineering 102 (or Civil Engineering
108), 156A. Introduction to mechanical functions of human body; skeletal
adaptations to optimize load transfer, mobility, and function. Dynamics
and kinematics. Fluid mechanics applications. Heat and mass transfer.
Power generation. Laboratory simulations and tests. Concurrently scheduled
with course CM240. Letter grading. |
C141L. Biomechanics Laboratory. (4) |
| Lecture, one hour; laboratory, three hours; outside
study, eight hours. Requisite: course CM140 or Mechanical and Aerospace
Engineering 156A. Hands-on laboratory pertaining to mechanical testing
and analysis of long bone specimens. Students, working in pairs, engage
in all aspects of procedures. Fundamentals include design and fabrication
of signal processing circuitry for use in data acquisition process,
including bridge completion circuits, amplifiers, and passive filters;
computerized data acquisition using Lab View and A/D input/output
(I/O) board; strain measurements on metallic and bone specimens. Finite
element analysis of structure under investigation; comparison of experimental,
theoretical, and computational results. Concurrently scheduled with
course C241L. Letter grading. |
CM145. Molecular Biotechnology for Engineers.
(4) |
| (Same as Chemical Engineering
CM145.) Lecture, four hours; discussion, one hour; outside study,
eight hours. Selected topics in molecular biology that form foundation
of biotechnology and biomedical industry today. Topics include recombinant
DNA technology, molecular research tools, manipulation of gene expression,
directed mutagenesis and protein engineering, DNA-based diagnostics
and DNA microarrays, antibody and protein-based diagnostics, genomics
and bioinformatics, isolation of human genes, gene therapy, and tissue
engineering. Concurrently scheduled with course CM245. Letter grading.
|
M150. Introduction to Micromachining and Microelectromechanical
Systems (MEMS). (4) |
| (Same as Electrical Engineering M150 and Mechanical
and Aerospace Engineering M180.) Lecture, three hours; outside study,
nine hours. Requisites: Chemistry 20A, 20L, Physics 1A, 1B, 1C, 4AL,
4BL. Corequisite: course M150L. Introduction to micromachining technologies
and microelectromechanical systems (MEMS). Methods of micromachining
and how these methods can be used to produce variety of MEMS, including
microstructures, microsensors, and microactuators. Students design
microfabrication processes capable of achieving desired MEMS device.
Letter grading. |
M150L. Introduction to Micromachining
and Microelectromechanical Systems (MEMS) Laboratory. (2) |
| (Same as Electrical Engineering M150L and Mechanical
and Aerospace Engineering M180L.) Lecture, one hour; laboratory, four
hours; outside study, one hour. Corequisite: course M150. Hands-on
introduction to micromachining technologies and microelectromechanical
systems (MEMS) laboratory. Methods of micromachining and how these
methods can be used to produce variety of MEMS, including microstructures,
microsensors, and microactuators. Students go through process of fabricating
MEMS device. Letter grading. |
C151. Nanofabrication of Biomedical
Systems Using Nonconventional Materials. (4) |
| Lecture, four hours; outside study, eight hours. Requisite:
course M150L (or Electrical Engineering M150L). Use of nontraditional
substrates and materials in fabrication of biomedical nanosystems.
Materials and fabrication issues, post-processing integration, compatibility
with standard processes, and standard fabrication environment. Packaging
concerns. Imaging and diagnostics techniques. Reliability issues.
Concurrently scheduled with course C251. Letter grading. |
C170.
Energy-Tissue Interactions. (4) |
| Lecture, three hours; outside study, nine hours. Requisites:
Electrical Engineering 172, 175, Life Sciences 3, Physics 17. Corequisite:
course C170L. Introduction to therapeutic and diagnostic use of energy
delivery devices in medical and dental applications, with emphasis
on understanding fundamental mechanisms underlying various types of
energy-tissue interactions. Concurrently scheduled with course C270.
Letter grading. |
C170L.
Introduction to Techniques in Studying Laser-Tissue Interaction. (2)
|
| Laboratory, four hours; outside study, two hours. Corequisite:
course C170. Introduction to simulation and experimental techniques
used in studying laser-tissue interactions. Topics include computer
simulations of light propagation in tissue, measuring absorption spectra
of tissue/tissue phantoms, making tissue phantoms, determination of
optical properties of different tissues, techniques of temperature
distribution measurements. Concurrently scheduled with course C270L.
Letter grading. |
C171. Laser-Tissue Interaction
II: Biologic Spectroscopy. (4) |
| Lecture, four hours; outside study, eight hours. Requisite:
course C170. Designed for physical sciences, life sciences, and engineering
majors. Introduction to optical spectroscopy principles, design of
spectroscopic measurement devices, optical properties of tissues,
and fluorescence spectroscopy biologic media. Concurrently scheduled
with course C271. Letter grading. |
CM180. Introduction to
Biomaterials. (4) |
| (Formerly numbered M180.) (Same as Materials Science
CM180.) Lecture, three hours; discussion, two hours; outside study,
seven hours. Requisites: Chemistry 20A, 20B, and 20L, or Materials
Science 14. Engineering materials used in medicine and dentistry for
repair and/or restoration of damaged natural tissues. Topics include
relationships between material properties, suitability to task, surface
chemistry, processing and treatment methods, and biocompatibility.
Concurrently scheduled with course CM280. Letter grading. |
C181. Biomaterials-Tissue
Interactions. (4) |
| Lecture, three hours; outside study, nine hours. Requisite:
course CM180. In-depth exploration of host cellular response to biomaterials:
vascular response, interface, and clotting, biocompatibility, animal
models, inflammation, infection, extracellular matrix, cell adhesion,
and role of mechanical forces. Concurrently scheduled with course
C281. Letter grading. |
C185. Introduction to Tissue
Engineering. (4) |
| Lecture, three hours; outside study, nine hours. Requisites:
course CM102 or CM202, Chemistry 20A, 20B, 20L. Tissue engineering
applies principles of biology and physical sciences with engineering
approach to regenerate tissues and organs. Guiding principles for
proper selection of three basic components for tissue engineering:
cells, scaffolds, and molecular signals. Concurrently scheduled with
course C285. Letter grading. |
M186A. Introduction to
Cybernetics, Biomodeling, and Biomedical Computing. (2) |
| (Formerly numbered M196A.) (Same as Computer Science
M186A and Cybernetics M186A.) Lecture, two hours. Requisites: Mathematics
31A, 31B, Program in Computing 10A. Strongly recommended for students
with potential interest in biomedical engineering/biocomputing fields
or in Cybernetics as a major. Introduction and survey of topics in
cybernetics, biomodeling, biocomputing, and related bioengineering
disciplines. Lectures presented by faculty currently performing research
in one of the areas; some sessions include laboratory tours. P/NP
grading. |
M186B. Computational Systems
Biology: Modeling and Simulation of Biological Systems. (5) |
| (Formerly numbered M196B.) (Same as Computer Science
M186B, Cybernetics M186B, and Medicine M186B.) Lecture, four hours;
discussion, one hour; laboratory, two hours. Requisite: Electrical
Engineering 102 or Mathematics 115A. Introduction to dynamic system
modeling, compartmental modeling, and computer simulation methods
for studying biomedical systems. Basics of numerical simulation algorithms,
translating biomodeling goals and data into mathematic models and
implementing them for simulation and analysis. Modeling software exploited
for class assignments in PC laboratory. Letter grading. |
CM186L. Biomedical
Systems/Biocybernetics Research Laboratory. (2 to 4) |
| (Formerly numbered CM196L.) (Same as Computer Science
CM186L and Cybernetics M186L.) Lecture, two hours; laboratory, two
hours. Requisite: course M186B. Special laboratory techniques and
experience in biocybernetics research. Laboratory instruments, their
use, design, and/or modification for research in life sciences. Special
research hardware, firmware, software. Use of simulation in experimental
laboratory. Laboratory automation and safety. Comprehensive experiment
design. Radioactive isotopes and kinetic studies. Experimental animals,
controls. Concurrently scheduled with course CM286L. Letter grading. |
188. Special Courses in Biomedical Engineering. (4) |
| (Formerly numbered 198.) Lecture, four hours; outside
study, eight hours. Special topics in biomedical engineering for undergraduate
students that are taught on experimental or temporary basis, such
as courses taught by resident and visiting faculty members. Letter
grading. |
| Graduate Division
(top of page) |
|
C201. Introduction to Biomedical
Engineering. (4)
|
| Lecture, four hours; laboratory, three hours; outside
study, five hours. Designed for physical sciences, life sciences,
and engineering students. Instead of presenting a general overview
of biomedical engineering, this course provides an in-depth, quantitative
analysis of a few topics in biomedical engineering. Concurrently scheduled
with course C101. Letter grading. |
|
CM202. Basic Human Biology for Biomedical
Engineers I. (4)
|
| (Same as Physiological Science CM204.) Lecture, three
hours; laboratory, two hours. Preparation: human molecular biology,
biochemistry, and cell biology. Not open for credit to Physiological
Science majors. Broad overview of basic biological activities and
organization of human body in system (organ/tissue) to system basis,
with particular emphasis on molecular basis. Modeling/simulation of
functional aspect of biological system included. Actual demonstration
of biomedical instruments, as well as visits to biomedical facilities.
Concurrently scheduled with course CM102. Letter grading. |
CM203. Basic Human
Biology for Biomedical Engineers II. (4) |
| (Same as Physiological Science CM203.) Lecture, three
hours; laboratory, two hours. Preparation: human molecular biology,
biochemistry, and cell biology. Not open for credit to Physiological
Science majors. Molecular-level understanding of human anatomy and
physiology in selected organ systems (digestive, skin, musculoskeletal,
endocrine, immune, urinary, reproductive). System-specific modeling/simulations
(immune regulation, wound healing, muscle mechanics and energetics,
acid-base balance, excretion). Functional basis of biomedical instrumentation
(dialysis, artificial skin, pathogen detectors, ultrasound, birth-control
drug delivery). Concurrently scheduled with course CM103. Letter grading.
|
M214A. Digital Speech Processing. (4)
|
| (Same as Electrical Engineering M214A.) Lecture, three
hours; laboratory, two hours; outside study, seven hours. Requisite:
Electrical Engineering 113. Theory and applications of digital processing
of speech signals. Mathematical models of human speech production
and perception mechanisms, speech analysis/synthesis. Techniques include
linear prediction, filter-bank models, and homomorphic filtering.
Applications to speech synthesis, automatic recognition, and hearing
aids. Letter grading. |
M215. Biochemical Reaction Engineering. (4) |
| (Same as Chemical Engineering CM215.) Lecture, four
hours; outside study, eight hours. Requisites: Chemical Engineering
101C and 106, or Chemistry 156. Use of previously learned concepts
of biophysical chemistry, thermodynamics, transport phenomena, and
reaction kinetics to develop tools needed for technical design and
economic analysis of biological reactors. Letter grading. |
M217. Biomedical Imaging. (4) |
| (Same as Electrical Engineering
M217.) Lecture, three hours; laboratory, two hours; outside study,
seven hours. Requisite: Electrical Engineering 114D or 211A. Mathematical
principles of medical imaging modalities: X-ray, computed tomography,
positron emission tomography, single photon emission computed tomography,
magnetic resonance imaging. Topics include basic principles of each
imaging system, image reconstruction algorithms, system configurations
and their effects on reconstruction algorithms, specialized imaging
techniques for specific applications such as flow imaging. Letter
grading. |
220. Introduction to Medical Informatics. (2) |
| Lecture, two hours; outside study, four hours. Designed
for graduate students. Introduction to research topics and issues
in medical informatics for students new to field. Definition of this
emerging field of study, current research efforts, and future directions
in research. Key issues in medical informatics to expose students
to different application domains, such as information system architectures,
data and process modeling, information extraction and representations,
information retrieval and visualization, health services research,
telemedicine. Emphasis on current research endeavors and applications.
S/U grading. |
221. Human Anatomy and Physiology for Medical Informatics. (4)
|
| Lecture, four hours; outside study, eight hours. Corequisite:
course 222. Designed for graduate students. Introduction to basic
human anatomy and physiology, with particular emphasis on visualization
of anatomy and physiology from imaging perspective. Topics include
chest, cardiac, neurology, gastrointestinal/genitourinary, and musculoskeletal
systems. Examination of basic imaging physics (magnetic resonance,
computed tomography, ultrasound, computed radiography) to provide
context for imaging modalities predominantly used to view human anatomy.
Geared toward nonphysicians who require more formal understanding
of human anatomy/physiology. Letter grading. |
222. Clinical Rotation Medical Informatics.
(2) |
| Lecture, two hours; laboratory, four hours. Corequisite:
course 221. Designed for graduate students. Clinical rotation through
medical imaging modalities and clinical environments. Exposure to
challenges of medical practice today and clinical usage of imaging,
including computed tomography, magnetic resonance, and other traditional
forms of image acquisition. Designed to provide students with real-world
exposure to practical applications of imaging and to reinforce human
anatomy and physiology concepts from other courses. Four hours per
week in clinical environments, observing clinicians in different medical
environments to gain appreciation of current practices, imaging, and
information systems. Participation in clinical noon conferences to
further broaden exposure and understanding of medical problems. S/U
grading. |
223A.
Programming Laboratory for Medical Informatics I. (4) |
| Lecture, two hours; laboratory, two hours. Designed
for graduate students. Programming laboratory to support coursework
in other medical informatics core curriculum courses. Exposure to
programming concepts for medical applications, with focus on basic
abstraction techniques used in image processing and medical information
system infrastructures (HL7, DICOM). Integrated with course 226 to
reinforce concepts presented with practical experience. Projects focus
on understanding medical networking issues and implementation of basic
protocols for health care environment, with emphasis on use of DICOM.
Letter grading. |
223B.
Programming Laboratory for Medical Informatics II. (4) |
| Lecture, two hours; laboratory, two hours. Requisite:
course 223A. Designed for graduate students. Programming laboratory
to support coursework in other medical informatics core curriculum
courses. Exposure to programming concepts for medical applications,
with focus on basic abstraction techniques used in image processing
and medical information system infrastructures (HL7, DICOM). Integrated
with courses 224A and 227 to reinforce concepts presented with practical
experience. Projects focus on medical image manipulation and decision
support systems. Letter grading. |
223C. Programming Laboratory
for Medical Informatics III. (4) |
| Lecture, two hours; laboratory, two hours. Requisite:
course 223B. Designed for graduate students. Programming laboratory
to support coursework in other medical informatics core curriculum
courses. Exposure to programming concepts for medical applications,
with focus on basic abstraction techniques used in image processing
and medical information system infrastructures (HL7, DICOM). Integrated
with courses 224B and 225 to reinforce concepts presented with practical
experience. Projects focus on medical image storage and retrieval.
Letter grading. |
224A. Physics and Informatics
of Medical Imaging. (4) |
| Lecture, four hours; laboratory, eight hours. Requisites:
Mathematics 33A, 33B. Designed for graduate students. Introduction
to principles of medical imaging and imaging informatics for nonphysicists.
Overview of core imaging modalities: computed radiography (CR), computed
tomography (CT), magnetic resonance (MR), and ultrasound (US). Emphasis
on physics of image formation and image reconstruction methods. Overview
of DICOM data models, basic medical image processing, content-based
image retrieval, PACS, and image data management. Geared toward nonphysicists
to provide basic understanding of issues related to basic medical
image acquisition. Current research efforts, with focus on clinical
applications and new types of information available through these
modalities. Letter grading. |
224B. Advanced Imaging
for Informatics. (4) |
| Lecture, four hours; outside study, eight hours. Requisite:
course 224A. Additional modalities and current research in imaging.
Topics include nuclear medicine, functional magnetic resonance imaging
(fMRI), MR diffusion/perfusion, and optical imaging, with focus on
image analysis and visualization tools. Basic physics principles behind
these newer imaging concepts, with exposure to seminal works. Current
research efforts, with focus on clinical applications and new types
of information available. Geared toward nonphysicists to provide basic
understanding of issues related to advanced medical image acquisition
and to understand functionality of imaging databases and image models
facilitating sharing of imaging data for clinical and research purposes.
Letter grading. |
M225. Bioseparations and
Bioprocess Engineering. (4) |
| (Same as Chemical Engineering CM225.) Lecture, four
hours; outside study, eight hours. Requisites: Chemical Engineering
101C and 103, or Chemistry 156. Separation strategies, unit operations,
and economic factors used to design processes for isolating and purifying
materials like whole cells, enzymes, food additives, or pharmaceuticals
that are products of biological reactors. Letter grading. |
226. Medical Knowledge
Representation. (4) |
| Seminar, four hours; outside study, eight hours. Designed
for graduate students. Issues related to medical knowledge representation
and its application in health care processes. Topics include data
structures used for representing knowledge (conceptual graphs, frame-based
models), different data models for representing spatio-temporal information,
rule-based implementations, current statistical methods for discovery
of knowledge (data mining, statistical classifiers, and hierarchical
classification), and basic information retrieval. Review of work in
constructing ontologies, with focus on problems in implementation
and definition. Common medical ontologies, coding schemes, and standardized
indices/terminologies (SNOMEF, UMLS, MeSH, LOINC). Letter grading.
|
227. Medical Information
Infrastructures and Internet Technologies. (4) |
| Lecture, four hours; outside study, eight hours. Designed
for graduate students. Introduction to networking, communications,
and information infrastructures in medical environment. Exposure to
basic concepts related to networking at several levels: low-level
(TCP/IP, services), medium-level (network topologies), and high-level
(distributed computing, Web-based services) implementations. Commonly
used medical communication protocols (HL7, DICOM) and current medical
information systems (HIS, RIS, PACS). Advances in networking, such
as wireless, Internet2/gigabit networks, peer-to-peer topologies.
Introduction to security and encryption in networked environments.
Letter grading. |
228. Medical Decision Making. (4) |
| Lecture, four hours; outside study, eight hours. Designed
for graduate students. Overview of issues related to medical decision
making. Introduction to concept of evidence-based medicine and decision
processes related to process of care and outcomes. Basic probability
and statistics to understand research results and evaluations, and
algorithmic methods for decision-making processes (Bayes theorem,
decision trees). Study design, hypothesis testing, and estimation.
Focus on technical advances in medical decision support systems and
expert systems, with review of classic and current research. Introduction
to common statistical and decision-making software packages to familiarize
students with current tools. S/U grading. |
230. Engineering Principles of Ultrasound. (4) |
| Lecture, three hours; discussion, one hour; outside
study, eight hours. Introduction to science and technology of acoustics
in biological systems, starting with physical acoustics, acoustic
wave (Helmholtz) equation, acoustic propagation and scattering in
homogeneous and inhomogeneous media, and acoustic attentuation and
davitation phenomena. Acoustic impedance, equivalent circuits, and
network models. Electroacoustic transducers (piezoelectric and MEMS)
and radiators. Acoustic generation, modulation, and pulse forming.
Acoustic noise mechanisms. Receiving and processing of acoustic waves
in presence of noise. Letter grading. |
CM240. Introduction to Biomechanics. (4) |
| (Same as Mechanical and Aerospace Engineering CM240.)
Lecture, four hours; outside study, eight hours. Requisites: Civil
Engineering 108 or Mechanical and Aerospace Engineering 102, 156A.
Introduction to mechanical functions of human body; skeletal adaptations
to optimize load transfer, mobility, and function. Dynamics and kinematics.
Fluid mechanics applications. Heat and mass transfer. Power generation.
Laboratory simulations and tests. Concurrently scheduled with course
CM140. Letter grading. |
C241L. Biomechanics Laboratory.
(4) |
| Lecture, one hour; laboratory, three hours; outside
study, eight hours. Requisite: course CM140 or Mechanical and Aerospace
Engineering 156A. Hands-on laboratory pertaining to mechanical testing
and analysis of long bone specimens. Students, working in pairs, engage
in all aspects of procedures. Fundamentals include design and fabrication
of signal processing circuitry for use in data acquisition process,
including bridge completion circuits, amplifiers, and passive filters;
computerized data acquisition using Lab View and A/D input/output
(I/O) board; strain measurements on metallic and bone specimens. Finite
element analysis of structure under investigation; comparison of experimental,
theoretical, and computational results. Concurrently scheduled with
course C141L. Letter grading. |
CM245. Molecular Biotechnology
for Engineers. (4) |
| (Same as Chemical Engineering CM245.) Lecture, four
hours; discussion, one hour; outside study, eight hours. Selected
topics in molecular biology that form foundation of biotechnology
and biomedical industry today. Topics include recombinant DNA technology,
molecular research tools, manipulation of gene expression, directed
mutagenesis and protein engineering, DNA-based diagnostics and DNA
microarrays, antibody and protein-based diagnostics, genomics and
bioinformatics, isolation of human genes, gene therapy, and tissue
engineering. Concurrently scheduled with course CM145. Letter grading.
|
M248. Introduction to Biological
Imaging. (4) |
| (Same as Biomedical Physics M248 and Pharmacology M248.)
Lecture, three hours; laboratory, one hour; outside study, seven hours.
Exploration of role of biological imaging in modern biology and medicine,
including imaging physics, instrumentation, image processing, and
applications of imaging for a range of modalities. Practical experience
provided through a series of imaging laboratories. Letter grading.
|
M250A. Microelectromechanical
Systems (MEMS) Fabrication. (4) |
| (Same as Electrical Engineering M250A and Mechanical
and Aerospace Engineering M280.) Lecture, three hours; discussion,
one hour; outside study, eight hours. Requisite: course M150L. Advanced
discussion of micromachining processes used to construct MEMS. Coverage
of many lithographic, deposition, and etching processes, as well as
their combination in process integration. Materials issues such as
chemical resistance, corrosion, mechanical properties, and residual/intrinsic
stress. Letter grading. |
M250B. Microelectromechanical Systems (MEMS) Device Physics and Design.
(4) |
| (Same as Electrical Engineering M250B and Mechanical
and Aerospace Engineering M282.) Lecture, three hours; discussion,
one hour; outside study, eight hours. Requisite: course M250A. Introduction
to MEMS design. Design methods, design rules, sensing and actuation
mechanisms, microsensors, and microactuators. Designing MEMS to be
produced with both foundry and nonfoundry processes. Computer-aided
design for MEMS. Design project required. Letter grading. |
C251. Nanofabrication of
Biomedical Systems Using Nonconventional Materials. (4) |
| Lecture, four hours; outside study, eight hours. Requisites:
course M150L (or Electrical Engineering M150L), M250B. Use of nontraditional
substrates and materials in fabrication of biomedical nanosystems.
Materials and fabrication issues, post-processing integration, compatibility
with standard processes, and standard fabrication environment. Packaging
concerns. Imaging and diagnostics techniques. Reliability issues.
Concurrently scheduled with course C151. Letter grading. |
257. Engineering Mechanics
of Motor Proteins and Cytoskeleton. (4) |
| Lecture, four hours; outside study, eight hours. Requisites:
Mathematics 32A, 32B, 33A, 33B, Life Sciences 3, Physics 1A, 1B, 1C.
Introduction to physics of motor proteins and cytoskeleton: mass,
stiffness and damping of proteins, thermal forces and diffusion, chemical
forces, polymer mechanics, structures of cytoskeletal filaments, mechanics
of cytoskeleton, polymerization of cytoskeletal filaments, force generation
by cytoskeletal filaments, active polymerization, motor protein structure
and operation. Emphasis on engineering perspective. Letter grading.
|
M259H. Biomechanics of
Traumatic Injury. (4) |
| (Same as Environmental Health Sciences M259H.) Lecture,
four hours; outside study, eight hours. Designed for graduate students.
Introduction to applied biomechanics of accidental injury causation
and prevention; discussion of mechanisms of injury that result in
bone and soft tissue trauma; discussion of mechanisms of healing for
effective rehabilitation after traumatic injury. Letter grading. |
M260. Neuroengineering.
(4) |
| (Formerly numbered 260.) (Same as Neuroscience M206.)
Lecture, four hours; laboratory, three hours; outside study, five
hours. Requisites: Mathematics 32A, Molecular, Cell, and Developmental
Biology 100, 171. Introduction to principles and technologies of neural
recording and stimulation. Neurophysiology; clinical electrophysiology
(EEG, evoked potentials, inverse problem, preoperative brain recording),
extracellular microelectrodes and recording (field potentials and
single units), chronic recording with extracellular electrodes; electrode
biocompatibility, tissue damage, electrode and cable survival; intracellular
recording and glass pipettes electrodes, iontophoresis; imaging neural
activity (Ca imaging, voltage-sensitive dyes), intrinsic optical imaging;
MRI, fMRI. Letter grading. |
M261A. Evaluation of Research
Literature in Neuroengineering. (2) |
| (Same as Neuroscience M212A.) Discussion, two hours.
Critical discussion and analysis of current literature related to
neuroengineering research. S/U grading. |
M261B. Evaluation of Research
Literature in Neuroengineering. (2) |
| (Same as Neuroscience M212B.) Discussion, two hours.
Critical discussion and analysis of current literature related to
neuroengineering research. S/U grading. |
M261C. Evaluation of Research
Literature in Neuroengineering. (2) |
| (Same as Neuroscience M212C.) Discussion, two hours.
Critical discussion and analysis of current literature related to
neuroengineering research. S/U grading. |
M263. Neuroanatomy: Structure
and Function of Nervous System. (4) |
| (Formerly numbered M263A.) (Same as Neuroscience M203.)
Lecture, three hours; discussion/laboratory, three hours. Anatomy
of central and peripheral nervous system at cellular histological
and regional systems level, with emphasis on contemporary experimental
approaches to morphological study of nervous system in discussions
of circuitry and neurochemical anatomy of major brain regions. Consideration
of representative vertebrate and invertebrate nervous systems. Letter
grading. |
C270. Energy-Tissue Interactions.
(4) |
| Lecture, three hours; outside study, nine hours. Requisites:
Electrical Engineering 172, 175, Life Sciences 3, Physics 17. Corequisite:
course C270L. Introduction to therapeutic and diagnostic use of energy
delivery devices in medical and dental applications, with emphasis
on understanding fundamental mechanisms underlying various types of
energy-tissue interactions. Concurrently scheduled with course C170.
Letter grading. |
C270L. Introduction to
Techniques in Studying Laser-Tissue Interaction. (2) |
| Laboratory, four hours; outside study, two hours. Corequisite:
course C270. Introduction to simulation and experimental techniques
used in studying laser-tissue interactions. Topics include computer
simulations of light propagation in tissue, measuring absorption spectra
of tissue/tissue phantoms, making tissue phantoms, determination of
optical properties of different tissues, techniques of temperature
distribution measurements. Concurrently scheduled with course C170L.
Letter grading. |
C271. Laser-Tissue Interaction
II: Biologic Spectroscopy. (4) |
| Lecture, four hours; outside study, eight hours. Requisite:
course C270. Designed for physical sciences, life sciences, and engineering
majors. Introduction to optical spectroscopy principles, design of
spectroscopic measurement devices, optical properties of tissues,
and fluorescence spectroscopy biologic media. Concurrently scheduled
with course C171. Letter grading. |
CM280. Introduction to
Biomaterials. (4) |
| (Same as Materials Science CM280.) Lecture, three hours;
discussion, two hours; outside study, seven hours. Requisites: Chemistry
20A, 20B, and 20L, or Materials Science 14. Engineering materials
used in medicine and dentistry for repair and/or restoration of damaged
natural tissues. Topics include relationships between material properties,
suitability to task, surface chemistry, processing and treatment methods,
and biocompatibility. Concurrently scheduled with course CM180. Letter
grading. |
C281. Biomaterials-Tissue
Interactions. (4) |
| Lecture, three hours; outside study, nine hours. Requisite:
course CM280. In-depth exploration of host cellular response to biomaterials:
vascular response, interface, and clotting, biocompatibility, animal
models, inflammation, infection, extracellular matrix, cell adhesion,
and role of mechanical forces. Concurrently scheduled with course
C181. Letter grading. |
282. Biomaterial Interfaces.
(4) |
| Lecture, four hours; laboratory, eight hours. Requisite:
course CM180 or CM280. Function, utility, and biocompatibility of
biomaterials depend critically on their surface and interfacial properties.
Discussion of morphology and composition of biomaterials and nanoscales,
mesoscales, and macroscales, techniques for characterizing structure
and properties of biomaterial interfaces, and methods for designing
and fabricating biomaterials with prescribed structure and properties
in vitro and in vivo. Letter grading. |
C285. Introduction to Tissue
Engineering. (4) |
| Lecture, three hours; outside study, nine hours. Requisites:
course CM102 or CM202, Chemistry 20A, 20B, 20L. Tissue engineering
applies principles of biology and physical sciences with engineering
approach to regenerate tissues and organs. Guiding principles for
proper selection of three basic components for tissue engineering:
cells, scaffolds, and molecular signals. Concurrently scheduled with
course C185. Letter grading. |
CM286L. Biomedical Systems/Biocybernetics
Research Laboratory. (2 to 4) |
| (Formerly numbered CM296L.) (Same as Computer Science
CM286L.) Lecture, two hours; laboratory, two hours. Requisite: course
M186B. Special laboratory techniques and experience in biocybernetics
research. Laboratory instruments, their use, design, and/or modification
for research in life sciences. Special research hardware, firmware,
software. Use of simulation in experimental laboratory. Laboratory
automation and safety. Comprehensive experiment design. Radioactive
isotopes and kinetic studies. Experimental animals, controls. Concurrently
scheduled with course CM186L. Letter grading. |
295A. Seminar: Research
Topics in Biomedical Engineering and Bioengineering -- Nanotechnology
Research. (1 to 4) |
| Seminar, one to four hours. Limited to biomedical engineering
graduate students. Advanced study and analysis of current topics in
bioengineering. Discussion of current research and literature in research
specialty of faculty member teaching course. Student presentation
of projects in research specialty. May be repeated for credit. S/U
grading. |
295B. Seminar: Research
Topics in Biomedical Engineering and Bioengineering -- Biomaterials
and Tissue Engineering Research. (1 to 4) |
| Seminar, one to four hours. Limited to biomedical engineering
graduate students. Advanced study and analysis of current topics in
bioengineering. Discussion of current research and literature in research
specialty of faculty member teaching course. Student presentation
of projects in research specialty. May be repeated for credit. S/U
grading. |
295C. Seminar: Research
Topics in Biomedical Engineering and Bioengineering -- Minimally Invasive
and Laser Research. (1 to 4) |
| Seminar, one to four hours. Limited to biomedical engineering
graduate students. Advanced study and analysis of current topics in
bioengineering. Discussion of current research and literature in research
specialty of faculty member teaching course. Student presentation
of projects in research specialty. May be repeated for credit. S/U
grading. |
295D. Seminar: Research
Topics in Biomedical Engineering and Bioengineering -- Hybrid Device
Research. (1 to 4) |
| Seminar, one to four hours. Limited to biomedical engineering
graduate students. Advanced study and analysis of current topics in
bioengineering. Discussion of current research and literature in research
specialty of faculty member teaching course. Student presentation
of projects in research specialty. May be repeated for credit. S/U
grading. |
295E. Seminar: Research
Topics in Biomedical Engineering and Bioengineering -- Molecular Cell
Bioengineering Research. (1 to 4) |
| Seminar, one to four hours. Limited to biomedical engineering
graduate students. Advanced study and analysis of current topics in
bioengineering. Discussion of current research and literature in research
specialty of faculty member teaching course. Student presentation
of projects in research specialty. May be repeated for credit. S/U
grading. |
M296A. Advanced Modeling
Methodology for Dynamic Biomedical Systems. (4) |
| (Same as Computer Science M296A and Medicine M270C.)
Lecture, four hours; outside study, eight hours. Requisite: Electrical
Engineering 141 or 142 or Mathematics 115A or Mechanical and Aerospace
Engineering 171A. Development of dynamic systems modeling methodology
for physiological, biomedical, pharmacological, chemical, and related
systems. Control system, multicompartmental, noncompartmental, and
input/output models, linear and nonlinear. Emphasis on model applications,
limitations, and relevance in biomedical sciences and other limited
data environments. Problem solving in PC laboratory. Letter grading.
|
M296B. Optimal Parameter Estimation and Experiment Design for Biomedical
Systems . (4) |
| (Same as Biomathematics M270, Computer Science M296B,
and Medicine M270D.) Lecture, four hours; outside study, eight hours.
Requisite: course M296A or Biomathematics 220. Estimation methodology
and model parameter estimation algorithms for fitting dynamic system
models to biomedical data. Model discrimination methods. Theory and
algorithms for designing optimal experiments for developing and quantifying
models, with special focus on optimal sampling schedule design for
kinetic models. Exploration of PC software for model building and
optimal experiment design via applications in physiology and pharmacology.
Letter grading. |
M296C. Advanced Topics
and Research in Biomedical Systems Modeling and Computing . (4) |
| (Same as Computer Science M296C and Medicine M270E.)
Lecture, four hours; outside study, eight hours. Requisite: course
M296A. Recommended: course M296B. Research techniques and experience
on special topics involving models, modeling methods, and model/computing
in biological and medical sciences. Review and critique of literature.
Research problem searching and formulation. Approaches to solutions.
Individual M.S.- and Ph.D.-level project training. Letter grading.
|
M296D. Introduction to
Computational Cardiology. (4) |
| (Same as Computer Science M296D.) Lecture, four hours;
outside study, eight hours. Requisite: course M196B. Introduction
to mathematical modeling and computer simulation of cardiac electrophysiological
process. Ionic models of action potential (AP). Theory of AP propagation
in one-dimensional and two-dimensional cardiac tissue. Simulation
on sequential and parallel supercomputers, choice of numerical algorithms,
to optimize accuracy and to provide computational stability. Letter
grading. |
298. Special Studies in
Biomedical Engineering. (4) |
| Lecture, four hours; outside study, eight hours. Study
of selected topics in biomedical engineering taught by resident and
visiting faculty members. Letter grading. |
299. Seminar: Biomedical
Engineering Topics. (2) |
| Seminar, two hours; outside study, four hours. Designed
for graduate biomedical engineering students. Seminar by leading academic
and industrial biomedical engineers from UCLA, other universities,
and biomedical engineering companies such as Baxter, Amgen, Medtronics,
and Guidant on development and application of recent technological
advances in the discipline. Exploration of cutting-edge developments
and challenges in wound healing models, stem cell biology, angiogenesis,
signal transduction, gene therapy, cDNA microarray technology, bioartificial
cultivation, nano- and micro-hybrid devices, scaffold engineering,
and bioinformatics. S/U grading. |
375. Teaching Apprentice
Practicum. (4) |
| Seminar, to be arranged. Preparation: apprentice personnel
employment as a teaching assistant, associate, or fellow. Teaching
apprenticeship under active guidance and supervision of a regular
faculty member responsible for curriculum and instruction at the University.
May be repeated for credit. S/U grading. |
596. Directed Individual
or Tutorial Studies . (2 to 8) |
| Tutorial, to be arranged. Limited to graduate biomedical
engineering students. Petition forms to request enrollment may be
obtained from program office. Supervised investigation of advanced
technical problems. S/U grading. |
597A. Preparation for M.S.
Comprehensive Examination . (2 to 12) |
| Tutorial, to be arranged. Limited to graduate biomedical
engineering students. Reading and preparation for M.S. comprehensive
examination. S/U grading. |
597B. Preparation for Ph.D.
Preliminary Examinations . (2 to 16) |
| Tutorial, to be arranged. Limited to graduate biomedical
engineering students. S/U grading. |
597C. Preparation for Ph.D.
Oral Qualifying Examination . (2 to 16) |
| Tutorial, to be arranged. Limited to graduate biomedical
engineering students. Preparation for oral qualifying examination,
including preliminary research on dissertation. S/U grading. |
598. Research for and Preparation
of M.S. Thesis . (2 to 12) |
| Tutorial, to be arranged. Limited to graduate biomedical
engineering students. Supervised independent research for M.S. candidates,
including thesis prospectus. S/U grading. |
599. Research for and Preparation
of Ph.D. Dissertation . (2 to 16) |
| Tutorial, to be arranged. Limited to graduate biomedical
engineering students. Usually taken after students have been advanced
to candidacy. S/U grading. |
|
